The Sinking City 2

The Sinking City 2 Consumables: Dolorocide, Regenerine, Lifesaver Kit, Night Ore

Track The Sinking City 2 consumables with direct uses, crafting recipes, when to spend Dolorocide, Regenerine Tonic, Lifesaver Kit, Night Ore, and survival resource priorities.

2026-08-26

The Sinking City 2 Consumables and Dolorocide Guide

Quick Answer

Dolorocide Pills are healing consumables. Use them when you need a direct health recovery and cannot safely reach a safe room. Do not spend every herb or chemical on healing, because Night Ore uses Chemicals x2 + Healing Herbs x3 and can recharge Night Shade for one automatic revive.

ConsumableMain UseBest Time to Use
Dolorocide PillsDirect healingAfter taking damage in a route where retreat is unsafe
Regenerine TonicStronger recovery / sustained healing roleBefore or after high-pressure fights when normal pills are not enough
Lifesaver KitEmergency recoveryBosses, long routes, and low-health recovery away from safe rooms
Night OreRecharges Night ShadeBefore bosses or long routes where one death would waste progress

Dolorocide Pills

Dolorocide is the basic healing item players search for when they need to survive a route without returning to safety. Treat it as a route stabilizer, not something to use after every small mistake.

Use Dolorocide when:

  • You are far from a safe room.
  • You have already collected a key item or upgrade.
  • The next room is likely to force combat.
  • Night Shade is not charged and you need direct health instead.

Save Dolorocide when:

  • You are close enough to retreat and save.
  • The next section is cleanup with low enemy pressure.
  • You need herbs and chemicals for Night Ore or stronger recovery items.

Regenerine Tonic and Lifesaver Kit

Regenerine Tonic and Lifesaver Kit should be treated as higher-value survival answers. If Dolorocide is your routine healing option, these are the items you hold for moments where losing the route would cost more time than spending the item.

ItemUse PriorityNotes
Regenerine TonicMedium-highBetter for routes where health pressure continues after the first hit
Lifesaver KitHighSave for bosses, long backtracking routes, and late-game danger

Night Ore Is a Consumable Too

Night Ore is not healing in the normal sense, but it belongs in your consumables plan because it protects Calvin from one fatal mistake through Night Shade.

Resource DecisionBetter Choice
Low health right nowDolorocide, Regenerine, or Lifesaver Kit
About to enter a bossRecharge Night Shade with Night Ore
Enough healing, Night Shade emptyCraft or use Night Ore
Herbs are scarceDo not craft Night Ore until you know the next route risk

Consumable Priority by Route

Route StateWhat to Carry
Normal explorationDolorocide plus one reserve heal
Flooded routeDolorocide and charged Night Shade if possible
Boss routeLifesaver Kit, best healing, and charged Night Shade
E.R.C. crate cleanupBasic healing; save rare items if a safe room is nearby
Late-game routeStrong healing plus Night Ore reserve

Common Mistakes

  • Spending Dolorocide after a small hit when a safe room is nearby.
  • Crafting Night Ore with your last Healing Herbs before checking health.
  • Entering a boss with healing but no charged Night Shade.
  • Using rare recovery items during low-risk cleanup.
  • Forgetting that consumables, ammo, and inventory space are all part of the same route budget.

FAQ

What is Dolorocide for?

Dolorocide Pills are healing consumables. Use them when you need direct recovery and retreating to a safe room would cost too much progress.

Should I save Dolorocide?

Yes, if a safe room is nearby or the route is low risk. Spend it when you are far from safety, carrying progress, or about to enter more combat.

Is Night Ore a healing item?

Not directly. Night Ore recharges Night Shade, which gives Calvin one automatic revive from a fatal blow.

Which consumable should I use before a boss?

Enter with your best healing available and recharge Night Shade with Night Ore before the fight.